Facile synthesis of enantiopure (-)-TAN1251A

被引:42
作者
Mizutani, H [1 ]
Takayama, J [1 ]
Soeda, Y [1 ]
Honda, T [1 ]
机构
[1] Hoshi Univ, Fac Pharmaceut Sci, Tokyo 1428501, Japan
关键词
D O I
10.1016/S0040-4039(02)00296-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Formal total synthesis of enantiopure (-)-TAN125lA, a muscarinic M, receptor antagonist, was achieved via a spirocyclic carbon-nitrogen bond formation by the use of aromatic oxidation with bis(acetoxy)iodobenzene as a key step. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2411 / 2414
页数:4
相关论文
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