共 21 条
Facile synthesis of enantiopure (-)-TAN1251A
被引:42
作者:
Mizutani, H
[1
]
Takayama, J
[1
]
Soeda, Y
[1
]
Honda, T
[1
]
机构:
[1] Hoshi Univ, Fac Pharmaceut Sci, Tokyo 1428501, Japan
关键词:
D O I:
10.1016/S0040-4039(02)00296-4
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
Formal total synthesis of enantiopure (-)-TAN125lA, a muscarinic M, receptor antagonist, was achieved via a spirocyclic carbon-nitrogen bond formation by the use of aromatic oxidation with bis(acetoxy)iodobenzene as a key step. (C) 2002 Elsevier Science Ltd. All rights reserved.
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页码:2411 / 2414
页数:4
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