Ten-year outcome of patients with very small abdominal aortic aneurysm

被引:20
作者
Biancari, F
Mosorin, M
Anttila, V
Satta, J
Juvonen, J
Juvonen, T
机构
[1] Oulu Univ Hosp, Dept Cardiothorac & Vasc Surg, Oulu 90221, Finland
[2] Kainuu Cent Hosp, Dept Internal Med, Kaajani, Finland
关键词
small abdominal aortic aneurysm; aneurysm rupture; aneurysm repair; ultrasonographic surveillance; beta-blockers;
D O I
10.1016/S0002-9610(01)00828-5
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: The long-term fate of very small abdominal aortic aneurysms (AAA) is not well known. Methods: Forty-one patients with asymptomatic small AAA (range 25 to 40 mm) underwent ultrasonographic surveillance. Results: The median follow-up period was 7.3 years. The median linear aneurysm expansion rate was 2.0 midyear (range 0 to 8.4). Three patients experienced aneurysm rupture (7.3%) which resulted in 1 patient, death. Thirteen patients underwent aneurysm repair (31.7%) and 1 patient died postoperatively (7.7%). The survival rate at 10-year follow-up was 59.0%. The survival rate free from aneurysm rupture and repair at 10-year follow-up was 69.9%. The median time for occurrence of aneurysm rupture was 4.9 years (range 1.8 to 10.5) and the need for aneurysm repair was 4.5 years (range 1.4 to 10.4). Conclusions: The fate of very small AAA is to slowly enlarge in size, sometimes threatening the patient's life. These observations underline the importance of continuous surveillance and the potential benefits of any medical treatment in this patient population. (C) 2002 Excerpta Medica, Inc. All rights reserved.
引用
收藏
页码:53 / 55
页数:3
相关论文
共 9 条
[1]   The fate of patients undergoing surveillance of small abdominal aortic aneurysms [J].
Galland, RB ;
Whiteley, MS ;
Magee, TR .
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 1998, 16 (02) :104-109
[2]  
Greenhalgh RM, 2000, EUR J VASC ENDOVASC, V19, P636
[3]   DETERMINATION OF THE EXPANSION RATE AND INCIDENCE OF RUPTURE OF ABDOMINAL AORTIC-ANEURYSMS [J].
LIMET, R ;
SAKALIHASSAN, N ;
ALBERT, A .
JOURNAL OF VASCULAR SURGERY, 1991, 14 (04) :540-548
[4]   Use of doxycycline to decrease the growth rate of abdominal aortic aneurysms: A randomized, double-blind, placebo-controlled pilot study [J].
Mosorin, M ;
Juvonen, J ;
Biancari, F ;
Satta, J ;
Surcel, HM ;
Leinonen, M ;
Saikku, P ;
Juvonen, T .
JOURNAL OF VASCULAR SURGERY, 2001, 34 (04) :606-610
[5]   PROGNOSIS OF ABDOMINAL AORTIC-ANEURYSMS - A POPULATION-BASED STUDY [J].
NEVITT, MP ;
BALLARD, DJ ;
HALLETT, JW .
NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (15) :1009-1014
[6]  
Powell JT, 1998, LANCET, V352, P1649
[7]   Cost-effectiveness of surgery for small abdominal aortic aneurysms on the basis of data from the United Kingdom small aneurysm trial [J].
Schermerhorn, ML ;
Birkmeyer, JD ;
Gould, DA ;
Cronenwett, JL .
JOURNAL OF VASCULAR SURGERY, 2000, 31 (02) :217-224
[8]   MMP inhibition in abdominal aortic aneurysms - Rationale for a prospective randomized clinical trial [J].
Thompson, RW ;
Baxter, BT .
INHIBITION OF MATRIX METALLOPROTEINASES: THERAPEUTIC APPLICATIONS, 1999, 878 :159-178
[9]   What is the long-term outcome for patients with very small abdominal aortic aneurysms? [J].
Watson, CJE ;
Walton, J ;
Shaw, E ;
Heather, B ;
Collin, J .
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 1997, 14 (04) :299-304