Multiorgan dysfunction and disseminated intravascular coagulation in children receiving lamotrigine and valproic acid

被引：41

作者：

Chattergoon, DS

McGuigan, MA

Koren, G

Hwang, P

Ito, S

机构：

[1] HOSP SICK CHILDREN,DIV CLIN PHARMACOL & TOXICOL,TORONTO,ON M5G 1X8,CANADA

[2] HOSP SICK CHILDREN,DIV NEUROL,TORONTO,ON M5G 1X8,CANADA

[3] HOSP SICK CHILDREN,DEPT PEDIAT,TORONTO,ON M5G 1X8,CANADA

[4] UNIV TORONTO,DEPT PHARMACOL,TORONTO,ON,CANADA

来源：

NEUROLOGY | 1997年 / 49卷 / 05期

关键词：

D O I：

10.1212/WNL.49.5.1442

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Two children developed multiorgan dysfunction with dis seminated intravascular coagulation 9 days after lamotrigine was added to their antiepileptic therapy, which included valproic acid. During the episodes, rhabdomyolysis was detected in one of them, while being seizure-free, suggesting that this adverse reaction may involve muscular tissue.

引用

页码：1442 / 1444

页数：3

共 9 条

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