Single molecule physics and chemistry

被引:49
作者
Bai, CL [1 ]
Wang, C
Xie, XS
Wolynes, PG
机构
[1] Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
[2] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 01238 USA
[3] Univ Illinois, Sch Chem Sci, Urbana, IL 61801 USA
关键词
D O I
10.1073/pnas.96.20.11075
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
New experiments using scanning probe microcopies and advanced optical methods allow us to study molecules as individuals, not just as populations, The findings of these studies not only include the confirmation of results expected from studies of bulk matter, but also give substantially new information concerning the complexity of biomolecules or molecules in a structured environment. The technique lays the groundwork for achieving the control of an individual molecule's motion. Ultimately, this work may lead to such practical applications as miniaturized sensors.
引用
收藏
页码:11075 / 11076
页数:2
相关论文
共 16 条
  • [11] MOERNER WE, 1996, ACCOUNTS CHEM RES, V26, P598
  • [12] Single-molecule vibrational spectroscopy and microscopy
    Stipe, BC
    Rezaei, MA
    Ho, W
    [J]. SCIENCE, 1998, 280 (5370) : 1732 - 1735
  • [13] INTERMITTENCY OF SINGLE-MOLECULE REACTION DYNAMICS IN FLUCTUATING ENVIRONMENTS
    WANG, J
    WOLYNES, P
    [J]. PHYSICAL REVIEW LETTERS, 1995, 74 (21) : 4317 - 4320
  • [14] Covalently functionalized nanotubes as nanometre-sized probes in chemistry and biology
    Wong, SS
    Joselevich, E
    Woolley, AT
    Cheung, CL
    Lieber, CM
    [J]. NATURE, 1998, 394 (6688) : 52 - 55
  • [15] Optical studies of single molecules at room temperature
    Xie, XS
    Trautman, JK
    [J]. ANNUAL REVIEW OF PHYSICAL CHEMISTRY, 1998, 49 : 441 - 480
  • [16] DIFFERENCES IN THE CHEMICAL-REACTIVITY OF INDIVIDUAL MOLECULES OF AN ENZYME
    XUE, QF
    YEUNG, ES
    [J]. NATURE, 1995, 373 (6516) : 681 - 683