The recently determined structure of the lipid-binding 'FYVE' domain provides several clues to the mode of interaction for this class of peripheral membrane proteins. However, the application of traditional modes of structural analysis to diffusible membrane-binding proteins exposes some limitations of these techniques.
机构:
Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA
Fruman, DA
Meyers, RE
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机构:Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA
Meyers, RE
Cantley, LC
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机构:Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA
机构:
Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA
Fruman, DA
Meyers, RE
论文数: 0引用数: 0
h-index: 0
机构:Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA
Meyers, RE
Cantley, LC
论文数: 0引用数: 0
h-index: 0
机构:Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA