Spontaneous remission of spasms in West syndrome - implications of viral infection

被引：36

作者：

Hattori, H ^{[1
]}

机构：

[1] Kyoto Univ, Sch Med, Dept Pediat, Kyoto 6068507, Japan

来源：

BRAIN & DEVELOPMENT | 2001年 / 23卷 / 07期

关键词：

West syndrome; neuroimmunology; cytokine; autoimmunity;

D O I：

10.1016/S0387-7604(01)00278-9

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

On a database of the Japanese medical literature between 1970 and 2000, there were 29 patients with West syndrome showing spontaneous remission. In 25/29 (86%) of the patients, spontaneous remission was preceded by viral infections, among which exanthema subitum predominated. In 16/29 (55%), the spasms recurred a median of 2 months later. However, some of the remaining infants attained lasting remission of the spasms. This link between viral infections and spontaneous remission suggests immuno-inflammatory processes underlie West syndrome in certain patients. Better understanding of such mechanisms may lead to a new therapeutic approach to West syndrome. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：705 / 707

页数：3

共 24 条

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