DNA and histone methylation in plants

被引：215

作者：

Tariq, M

Paszkowski, J

机构：

[1] Ctr Mol Biol, D-69120 Heidelberg, Germany

[2] Univ Geneva, Lab Plant Genet, CH-1211 Geneva 4, Switzerland

来源：

TRENDS IN GENETICS | 2004年 / 20卷 / 06期

关键词：

D O I：

10.1016/j.tig.2004.04.005

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Heritable patterns of gene activity and gene silencing arise by the formation and the propagation of specific chromatin states that restrict or permit gene expression. In mammals and in plants, restrictive heterochromatin is associated with the hypermethylation of DNA at CG sites and with the specific modification of histones, such as the methylation of histone H3 at lysine 9 (H3K9(Me)). In addition to CG methylation, plant nuclear DNA packaged in restrictive chromatin is also usually methylated in cytosines outside a CG sequence context. The functional relationship between an unexpectedly complex plant DNA-methylation system and histone modifications that lead to chromatin compaction and gene silencing is under intense scrutiny. The results of recent studies indicate intriguing links between chromatin remodeling, histone methylation, DNA methylation and RNA interference.

引用

收藏

页码：244 / 251

页数：8

相关论文

共 78 条

[1] The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly [J].

Ahmad, K ;

Henikoff, S .

MOLECULAR CELL, 2002, 9 (06) :1191-1200

[2] ATX-1, an Arabidopsis homolog of trithorax, activates flower homeotic genes [J].

Alvarez-Venegas, R ;

Pien, S ;

Sadder, M ;

Witmer, X ;

Grossniklaus, U ;

Avramova, Z .

CURRENT BIOLOGY, 2003, 13 (08) :627-637

[3] HDA6, a putative histone deacetylase needed to enhance DNA methylation induced by double-stranded RNA [J].

Aufsatz, W ;

Mette, MF ;

van der Winden, J ;

Matzke, M ;

Matzke, AJM .

EMBO JOURNAL, 2002, 21 (24) :6832-6841

[4] RNA-directed DNA methylation in Arabidopsis [J].

Aufsatz, W ;

Mette, MF ;

van der Winden, J ;

Matzke, AJM ;

Matzke, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 :16499-16506

[5] Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain [J].

Bannister, AJ ;

Zegerman, P ;

Partridge, JF ;

Miska, EA ;

Thomas, JO ;

Allshire, RC ;

Kouzarides, T .

NATURE, 2001, 410 (6824) :120-124

[6] Arabidopsis cmt3 chromomethylase mutations block non-CG methylation and silencing of an endogenous gene [J].

Bartee, L ;

Malagnac, F ;

Bender, J .

GENES & DEVELOPMENT, 2001, 15 (14) :1753-1758

[7] Two Arabidopsis methylation-deficiency mutations confer only partial effects on a methylated endogenous gene family [J].

Bartee, L ;

Bender, J .

NUCLEIC ACIDS RESEARCH, 2001, 29 (10) :2127-2134

[8] Vernalization requires epigenetic silencing of FLC by histone methylation [J].

Bastow, R ;

Mylne, JS ;

Lister, C ;

Lippman, Z ;

Martienssen, RA ;

Dean, C .

NATURE, 2004, 427 (6970) :164-167

[9] The Arabidopsis thaliana genome contains at least 29 active genes encoding SET domain proteins that can be assigned to four evolutionarily conserved classes [J].

Baumbusch, LO ;

Thorstensen, T ;

Krauss, V ;

Fischer, A ;

Naumann, K ;

Assalkhou, R ;

Schulz, I ;

Reuter, G ;

Aalen, RB .

NUCLEIC ACIDS RESEARCH, 2001, 29 (21) :4319-4333

[10] DNA methylation patterns and epigenetic memory [J].

Bird, A .

GENES & DEVELOPMENT, 2002, 16 (01) :6-21

← 1 2 3 4 5 6 7 8 →