Artecoll granuloma: A rare adverse reaction induced by microimplant in the treatment of neck wrinkles

BACKGROUND. Artecoll is now being widely used as an injectable aesthetic microimplant for the treatment of wrinkles because of its long-lasting cosmetic effects and the rarity of late complications, including foreign body granulomas. Recently, however, several cases of Artecoll-induced granulomas on the face have been reported, especially in patients receiving overly superficial or overly correcting implants. METHODS AND RESULTS. A 50-year-old Korean woman who had been treated with Artecoll for the correction of the neck wrinkles presented 4 years later with an extensive Artecoll-induced foreign body granuloma along the injection sites in the neck. After three intralesional injections of triamcinolone acetonide, the lesions had almost disappeared. CONCLUSION. To our knowledge, this case is the first report of an extensive Artecoll-induced granuloma on the neck. Our findings suggest that Artecoll not be used as implant material in thin and constantly movable skin, such as that of the neck.