Key stages in mammary gland development - Molecular mechanisms involved in the formation of the embryonic mammary gland

被引：134

作者：

Hens, JR ^{[1
]}

Wysolmerski, JJ

机构：

[1] Yale Univ, Sch Med, Dept Internal Med, Sect Endocrinol & Metab, New Haven, CT 06510 USA

[2] Anlyan Ctr Med Res & Educ, New Haven, CT USA

来源：

BREAST CANCER RESEARCH | 2005年 / 7卷 / 05期

关键词：

D O I：

10.1186/bcr1306

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The development of the embryonic mammary gland involves communication between the epidermis and mesenchyme and is coordinated temporally and spatially by various signaling pathways. Although many more genes are likely to control mammary gland development, functional roles have been identified for Wnt, fibroblast growth factor, and parathyroid hormone-related protein signaling. This review describes what is known about the molecular mechanisms that regulate embryonic mammary gland development.

引用

页码：220 / 224

页数：5

共 22 条

[1] Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome
Bamshad, M
Lin, RC
Law, DJ
Watkins, WS
Krakowiak, PA
Moore, ME
Franceschini, P
Lala, R
Holmes, LB
Gebuhr, TC
Bruneau, BG
Schinzel, A
Seidman, JG
Seidman, CE
Jorde, LB
[J]. NATURE GENETICS, 1997, 16 (03) : 311 - 315
[2] p190-B RhoGAP regulates mammary ductal morphogenesis
Chakravarty, G
Hadsell, D
Buitrago, W
Settleman, J
Rosen, JM
[J]. MOLECULAR ENDOCRINOLOGY, 2003, 17 (06) : 1054 - 1065
[3] Microarray analysis of Tbx2-directed gene expression:: a possible role in osteogenesis
Chen, JR
Zhong, Q
Wang, J
Cameron, RS
Borke, JL
Isales, CM
Bollag, RJ
[J]. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2001, 177 (1-2) : 43 - 54
[4] Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis
Chu, EY
Hens, J
Andl, T
Kairo, A
Yamaguchi, TP
Brisken, C
Glick, A
Wysolmerski, JJ
Millar, SE
[J]. DEVELOPMENT, 2004, 131 (19): : 4819 - 4829
[5] The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1
Coletta, RD
Christensen, K
Reichenberger, KJ
Lamb, J
Micomonaco, D
Huang, LL
Wolf, DM
Müller-Tidow, C
Golub, TR
Kawakami, K
Ford, HL
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (17) : 6478 - 6483
[6] Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome
Davenport, TG
Jerome-Majewska, LA
Papaioannou, VE
[J]. DEVELOPMENT, 2003, 130 (10): : 2263 - 2273
[7] Dunbar ME, 1999, DEVELOPMENT, V126, P3485
[8] Interactions between FGF and Wnt signals and Tbx3 gene expression in mammary gland initiation in mouse embryos
Eblaghie, MC
Song, SJ
Kim, JY
Akita, K
Tickle, C
Jung, HS
[J]. JOURNAL OF ANATOMY, 2004, 205 (01) : 1 - 13
[9] Foley J, 2001, DEVELOPMENT, V128, P513
[10] Signaling pathways in mammary gland development
Hennighausen, L
Robinson, GW
[J]. DEVELOPMENTAL CELL, 2001, 1 (04) : 467 - 475

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