Src autoinhibition: let us count the ways

被引：49

作者：

Hubbard, SR ^{[1
]}

机构：

[1] NYU, Sch Med, Dept Pharmacol, New York, NY 10016 USA

[2] NYU, Sch Med, Skirball Inst Biomol Med, New York, NY 10016 USA

来源：

NATURE STRUCTURAL BIOLOGY | 1999年 / 6卷 / 08期

关键词：

D O I：

10.1038/11468

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Src family tyrosine kinases are key cellular signaling enzymes whose catalytic activities are tightly controlled, Recent structural and mutational studies have revealed additional intricacies in the autoinhibitory mechanisms by which catalytic activity is repressed.

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收藏

页码：711 / 714

页数：4

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