Visible Light-Induced Aerobic Oxyamidation of Indoles: A Photocatalytic Strategy for the Preparation of Tetrahydro-5H-indolo[2,3-b]quinolinols

被引:47
作者
An, Jing [1 ]
Zou, You-Quan [1 ]
Yang, Qing-Qing [1 ]
Wang, Qiang [1 ]
Xiao, Wen-Jing [1 ]
机构
[1] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Hubei, Peoples R China
基金
美国国家科学基金会;
关键词
aerobic oxidation; indoles; oxyamidation; visible light photocatalysis; PHOTOREDOX CATALYSIS; SINGLET OXYGEN; ORGANIC-SYNTHESIS; PHOTOSENSITIZED OXYGENATION; PENICILLIUM-EXPANSUM; TRYPTOPHAN; OXIDATION; FUNCTIONALIZATION; CYCLOADDITIONS; METABOLITES;
D O I
10.1002/adsc.201300175
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A visible light-induced, aerobic oxyamidation reaction of indoles, using air as the sole oxidant, has been developed. This process serves as a photocatalytic strategy to generate efficiently tetrahydro-5H-indolo[2,3-b]quinolinols, which may have interesting biological and pharmacological activities owing to their privileged indoline structure.
引用
收藏
页码:1483 / 1489
页数:7
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