79Br NMR spectroscopy as a practical tool for kinetic analysis

被引:6
作者
Chan, Si Jia [1 ]
Howe, Andrew G. [1 ]
Hook, James M. [2 ]
Harper, Jason B. [1 ]
机构
[1] Univ New S Wales, Sch Chem, Sydney, NSW 2052, Australia
[2] Univ New S Wales, Analyt Ctr, Sydney, NSW 2052, Australia
关键词
NMR; Br-79; H-1; kinetic analysis; Menschutkin reaction; BROMIDE ION; LIQUID; DYNAMICS;
D O I
10.1002/mrc.2401
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Br-79 NMR spectroscopy has been used to monitor a series of reactions in which the bromide ion is produced, including the Menschutkin reaction of pyridine with a range of substituted benzyl bromides and a Heck coupling process. In cases where the process could also be monitored using H-1 NMR spectroscopy, the kinetic analyses using heteronuclear magnetic resonance spectroscopy were shown to be completely consistent. Both the utility of the process in following reactions which may be difficult to analyse using other techniques and the practical limitations associated with solvent choice are discussed. Copyright (c) 2009 John Wiley & Sons, Ltd.
引用
收藏
页码:342 / 347
页数:6
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