Rfam 11.0: 10 years of RNA families

被引：603

作者：

Burge, Sarah W. ^{[1
]}

Daub, Jennifer ^{[1
]}

Eberhardt, Ruth ^{[1
]}

Tate, John ^{[1
]}

Barquist, Lars ^{[1
]}

Nawrocki, Eric P. ^{[2
]}

Eddy, Sean R. ^{[2
]}

Gardner, Paul P. ^{[3
]}

Bateman, Alex ^{[1
]}

机构：

[1] Wellcome Trust Sanger Inst, Hinxton CB10 1SA, Cambs, England

[2] Howard Hughes Med Inst, Ashburn, VA 20147 USA

[3] Univ Canterbury, Sch Biol Sci, Christchurch 8140, New Zealand

来源：

NUCLEIC ACIDS RESEARCH | 2013年 / 41卷 / D1期

基金：

英国惠康基金;

关键词：

ANNOTATION; SEARCH;

D O I：

10.1093/nar/gks1005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Rfam database (available via the website at http://rfam.sanger.ac.uk and through our mirror at http://rfam.janelia.org) is a collection of non-coding RNA families, primarily RNAs with a conserved RNA secondary structure, including both RNA genes and mRNA cis-regulatory elements. Each family is represented by a multiple sequence alignment, predicted secondary structure and covariance model. Here we discuss updates to the database in the latest release, Rfam 11.0, including the introduction of genome-based alignments for large families, the introduction of the Rfam Biomart as well as other user interface improvements. Rfam is available under the Creative Commons Zero license.

引用

页码：D226 / D232

页数：7

共 19 条

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