N-arylpiperazinone inhibitors of farnesyltransferase:: Discovery and biological activity

被引：57

作者：

Williams, TM ^{[1
]}

Bergman, JM

Brashear, K

Breslin, MJ

Dinsmore, CJ

Hutchinson, JH

MacTough, SC

Stump, CA

Wei, DD

Zartman, CB

Bogusky, MJ

Culberson, JC

Buser-Doepner, C

Davide, J

Greenberg, IB

Hamilton, KA

Koblan, KS

Kohl, NE

Liu, DM

Lobell, RB

Mosser, SD

O'Neill, TJ

Rands, E

Schaber, MD

Wilson, F

Senderak, E

Motzel, SL

Gibbs, JB

Graham, SL

Heimbrook, DC

Hartman, GD

Oliff, AI

Huff, JR

机构：

[1] Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA

[2] Merck Res Labs, Dept Canc Res, W Point, PA 19486 USA

[3] Merck Res Labs, Dept Mol Syst, W Point, PA 19486 USA

[4] Merck Res Labs, Dept Biometr Res, W Point, PA 19486 USA

[5] Merck Res Labs, Dept Lab Anim Resources, W Point, PA 19486 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1999年 / 42卷 / 19期

关键词：

D O I：

10.1021/jm990254z

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：3779 / 3784

页数：6

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