Murine models do not recapitulate the pathophysiology of age-related venous thrombosis in humans

被引：13

作者：

Cardenas, J. C. ^{[1
]}

Aleman, M. M. ^{[1
]}

Wang, J. -G. ^{[1
]}

Whinna, H. C. ^{[1
,2
]}

Wolberg, A. S. ^{[1
,2
]}

Church, F. C. ^{[1
,2
]}

机构：

[1] Univ N Carolina, Sch Med, Dept Pathol & Lab Med, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Sch Med, UNC McAllister Heart Inst, Chapel Hill, NC 27599 USA

来源：

JOURNAL OF THROMBOSIS AND HAEMOSTASIS | 2013年 / 11卷 / 05期

关键词：

D O I：

10.1111/jth.12189

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

收藏

页码：990 / 992

页数：3

相关论文

共 17 条

[1]

[Anonymous], 2008, SURG GEN CALL ACTION

[2]

Overexpression of the Cell Cycle Inhibitor p16INK4a Promotes a Prothrombotic Phenotype Following Vascular Injury in Mice [J].

Cardenas, Jessica C. ;

Owens, A. Phillip, III ;

Krishnamurthy, Janakiraman ;

Sharpless, Norman E. ;

Whinna, Herbert C. ;

Church, Frank C. .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2011, 31 (04) :827-U239

[3]

Critical Review of Mouse Models of Venous Thrombosis [J].

Diaz, Jose A. ;

Obi, Andrea T. ;

Myers, Daniel D., Jr. ;

Wrobleski, Shirley K. ;

Henke, Peter K. ;

Mackman, Nigel ;

Wakefield, Thomas W. .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2012, 32 (03) :556-562

[4]

Age-dependency of thrombin generation measured by means of calibrated automated thrombography (CAT) [J].

Haidl, Harald ;

Cimenti, Christina ;

Leschnik, Bettina ;

Zach, Doris ;

Muntean, Wolfgang .

THROMBOSIS AND HAEMOSTASIS, 2006, 95 (05) :772-775

[5]

Effect of ageing on the murine venous circulation [J].

Hemmeryckx, Bianca ;

Emmerechts, Jan ;

Bovill, Edwin G. ;

Hoylaerts, Marc F. ;

Lijnen, H. R. .

HISTOCHEMISTRY AND CELL BIOLOGY, 2012, 137 (04) :537-546

[6]

Progression of the Prothrombotic State in Aging Bmal1-Deficient Mice [J].

Hemmeryckx, Bianca ;

Van Hove, Cor E. ;

Fransen, Paul ;

Emmerechts, Jan ;

Kauskot, Alexandre ;

Bult, Hidde ;

Lijnen, H. Roger ;

Hoylaerts, Marc F. .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2011, 31 (11) :2552-U471

[7]

An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations [J].

Kregel, Kevin C. ;

Zhang, Hannah J. .

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2007, 292 (01) :R18-R36

[8]

Mutation of the mouse klotho gene leads to a syndrome resembling ageing [J].

Kuroo, M ;

Matsumura, Y ;

Aizawa, H ;

Kawaguchi, H ;

Suga, T ;

Utsugi, T ;

Ohyama, Y ;

Kurabayashi, M ;

Kaname, T ;

Kume, E ;

Iwasaki, H ;

Iida, A ;

ShirakiIida, T ;

Nishikawa, S ;

Nagai, R ;

Nabeshima, Y .

NATURE, 1997, 390 (6655) :45-51

[9]

HYPERCOAGULABILITY IN CENTENARIANS - THE PARADOX OF SUCCESSFUL AGING [J].

MARI, D ;

MANNUCCI, PM ;

COPPOLA, R ;

BOTTASSO, B ;

BAUER, KA ;

ROSENBERG, RD .

BLOOD, 1995, 85 (11) :3144-3149

[10]

Peripheral blood leukocyte populations in the elderly with and without periodontal disease [J].

McArthur, WP ;

Bloom, K ;

Taylor, M ;

Wheeler, T ;

Smith, J ;

Magnusson, NI .

JOURNAL OF CLINICAL PERIODONTOLOGY, 1996, 23 (09) :846-852