Blood vessels engineered from human cells

被引:56
作者
Gong, Zhaodi
Niklason, Laura E. [1 ]
机构
[1] Duke Univ, Dept Anesthesia, Durham, NC 27708 USA
[2] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
关键词
D O I
10.1016/j.tcm.2006.02.006
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Human vascular tissue engineering has progressed substantially over the past decade. Issues remain as to the optimum culture scaffold and cell source that should be used for arterial regeneration. hi addition, limitations in replicative life span of adult human cells as compared with young animal cells have made human vascular tissue engineering more challenging. Despite these obstacles, several strategies for generating replacement vessels have progressed to clinical trials.
引用
收藏
页码:153 / 156
页数:4
相关论文
共 36 条
  • [31] The tissue-engineered small-diameter artery
    Tranquillo, RT
    [J]. REPARATIVE MEDICINE: GROWING TISSUES AND ORGANS, 2002, 961 : 251 - 254
  • [32] RECONSTITUTION OF THE VASCULAR WALL INVITRO - A NOVEL MODEL TO STUDY INTERACTIONS BETWEEN ENDOTHELIAL AND SMOOTH-MUSCLE CELLS
    VANBUULWORTELBOER, MF
    BRINKMAN, HJM
    DINGEMANS, KP
    DEGROOT, PG
    VANAKEN, WG
    VANMOURIK, JA
    [J]. EXPERIMENTAL CELL RESEARCH, 1986, 162 (01) : 151 - 158
  • [33] A BLOOD-VESSEL MODEL CONSTRUCTED FROM COLLAGEN AND CULTURED VASCULAR CELLS
    WEINBERG, CB
    BELL, E
    [J]. SCIENCE, 1986, 231 (4736) : 397 - 400
  • [34] Tissue-engineered microvessels on three-dimensional biodegradable scaffolds using human endothelial progenitor cells
    Wu, X
    Rabkin-Aikawa, E
    Guleserian, KJ
    Perry, TE
    Masuda, Y
    Sutherland, FWH
    Schoen, FJ
    Mayer, JE
    Bischoff, J
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2004, 287 (02): : H480 - H487
  • [35] Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction
    Yoon, YS
    Wecker, A
    Heyd, L
    Park, JS
    Tkebuchava, T
    Kusano, K
    Hanley, A
    Scadova, H
    Qin, GJ
    Cha, DH
    Johnson, KL
    Aikawa, R
    Asahara, T
    Losordo, DW
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (02) : 326 - 338
  • [36] YUAN F, 1994, CANCER RES, V54, P4564