Superior methodology for the nitration of simple aromatic compounds

被引：69

作者：

Smith, K ^{[1
]}

Musson, A ^{[1
]}

DeBoos, GA ^{[1
]}

机构：

[1] ZENECA,HUDDERSFIELD WORK,HUDDERSFIELD HD2 1FF,W YORKSHIRE,ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 04期

关键词：

D O I：

10.1039/cc9960000469

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Simple aromatic compounds such as benzene, alkylbenzenes and halogenobenzenes are nitrated in quantitative yield and with high para-selectivity in a solvent free process by use of a stoichiometric quantity of nitric acid and acetic anhydride at 0-20 degrees C in the presence of zeolite beta as catalyst; the zeolite can be recycled and the only by-product is acetic acid, which is easily separated from the nitration product by distillation; the process is inexpensive and highly convenient and represents the best currently available methodology for the clean syntheses of a range of simple nitroaromatic compounds.

引用

页码：469 / 470

页数：2