Optimization of conductivity detection of low-molecular-mass anions in capillary zone electrophoresis

被引：36

作者：

Katzmayr, MU ^{[1
]}

Klampfl, CW ^{[1
]}

Buchberger, W ^{[1
]}

机构：

[1] Johannes Kepler Univ, Dept Analyt Chem, A-4040 Linz, Austria

来源：

JOURNAL OF CHROMATOGRAPHY A | 1999年 / 850卷 / 1-2期

关键词：

conductivity detection; detection; electrophoresis; background electrolyte composition; organic acids; inorganic anions;

D O I：

10.1016/S0021-9673(99)00168-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The optimization of background electrolyte compositions for capillary zone electrophoresis in combination with conductivity detection focusing on maximal detector response is discussed. A theoretical approach pointing out the influence of the electrolyte co- and counter-ion mobilities on the detector signal has been developed. Using this model, running buffer compositions providing optimum SIN ratios for the selected analytes could be calculated. The results derived from these examinations have been verified by experimental investigations, namely the determination of inorganic and organic anionic solutes. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：355 / 362

页数：8

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