Vaginal Lactobacillus isolates inhibit uropathogenic Escherichia coli

被引：21

作者：

Atassi, F

Brassart, D

Grob, P

Graf, F

Servin, AL ^{[1
]}

机构：

[1] Univ Paris 11, Fac Pharm, INSERM, Unite 756, F-92296 Chatenay Malabry, France

[2] Medinova AG, Zurich, Switzerland

来源：

FEMS MICROBIOLOGY LETTERS | 2006年 / 257卷 / 01期

关键词：

uropathogenic Escherichia coli; Lactobacillus; antibacterial;

D O I：

10.1111/j.1574-6968.2006.00163.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The purpose of this study was to investigate the antibacterial activities of Lactobacillus jensenii KS119.1 and KS121.1, and Lactobacillus gasserii KS120.1 and KS124.3 strains isolated from the vaginal microflora of healthy women, against uropathogenic, diffusely adhering Afa/Dr Escherichia coli (Afa/Dr DAEC) strains IH11128 and 7372 involved in recurrent cystitis. We observed that some of the Lactobacillus isolates inhibited the growth and decreased the viability of E. coli IH11128 and 7372. In addition, we observed that adhering Lactobacillus strains inhibited adhesion of E. coli IH11128 onto HeLa cells, and inhibited internalization of E. coli IH11128 within HeLa cells.

引用

页码：132 / 138

页数：7