CNTRICS Final Task Selection: Executive Control

被引:101
作者
Barch, Deanna M. [1 ,2 ]
Braver, Todd S. [1 ]
Carter, Cameron S. [3 ,4 ]
Poldrack, Russell A. [5 ]
Robbins, Trevor W. [6 ]
机构
[1] Washington Univ, Dept Psychol, St Louis, MO 63130 USA
[2] Washington Univ, Dept Radiol, St Louis, MO 63130 USA
[3] Univ Calif Davis, Dept Psychiat, Davis, CA 95616 USA
[4] Univ Calif Davis, Dept Psychol, Davis, CA 95616 USA
[5] Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA 90024 USA
[6] Univ Cambridge, Dept Expt Psychol, Cambridge CB2 3EB, England
关键词
ANTERIOR CINGULATE CORTEX; REACTION-TIME-TASK; PREFRONTAL SEROTONIN DEPLETION; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; OBSESSIVE-COMPULSIVE DISORDER; COGNITIVE CONTROL MECHANISMS; SET-SHIFTING PERFORMANCE; ERROR-RELATED NEGATIVITY; SPATIAL WORKING-MEMORY; MEDIAL FRONTAL-CORTEX;
D O I
10.1093/schbul/sbn154
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The third meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) was focused on selecting promising measures for each of the cognitive constructs selected in the first CNTRICS meeting. In the domain of executive control, the 2 constructs of interest were "rule generation and selection" and "dynamic adjustments in control." CNTRICS received 4 task nominations for each of these constructs, and the breakout group for executive control evaluated the degree to which each of these tasks met prespecified criteria. For rule generation and selection, the breakout group for executive control recommended the intradimensional/extradimensional shift task and the switching Stroop for translation for use in clinical trial contexts in schizophrenia research. For dynamic adjustments in control, the breakout group recommended conflict and error adaptation in the Stroop and the stop signal task for translation for use in clinical trials. This article describes the ways in which each of these tasks met the criteria used by the breakout group to recommend tasks for further development.
引用
收藏
页码:115 / 135
页数:21
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