Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors

被引：125

作者：

Ingalls, RR ^{[1
]}

Heine, H ^{[1
]}

Lien, E ^{[1
]}

Yoshimura, A ^{[1
]}

Golenbock, D ^{[1
]}

机构：

[1] Boston Univ, Med Ctr, Sch Med, Maxwell Finland Lab Infect Dis, Boston, MA 02118 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 1999年 / 13卷 / 02期

关键词：

D O I：

10.1016/S0891-5520(05)70078-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The ability of a host to sense invasion by a pathogenic organism, and to respond appropriately to control infection, is paramount to survival. To that end, an array of receptors and binding proteins has evolved as part of the innate immune system to detect Gram-negative bacteria. This article reviews the role of CD14, other LPS binding proteins, and the Toll family of receptors in the innate recognition of bacterial lipopolysaccharide.

引用

页码：341 / +

页数：14

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