Magnetic bead handling on-chip: new opportunities for analytical applications

被引:669
作者
Gijs, MAM [1 ]
机构
[1] Swiss Fed Inst Technol, Inst Microelect & Microsyst, CH-1015 Lausanne, Switzerland
关键词
microfluidics; magnetic bead handling; magnetic bead assay; magnetic bead labeling; magnetic supraparticle structure;
D O I
10.1007/s10404-004-0010-y
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
This review describes recent advances in the handling and manipulation of magnetic particles in microfluidic systems. Starting from the properties of magnetic nanoparticles and microparticles, their use in magnetic separation, immuno-assays, magnetic resonance imaging, drug delivery, and hyperthermia is discussed. We then focus on new developments in magnetic manipulation, separation, transport, and detection of magnetic microparticles and nanoparticles in microfluidic systems, pointing out the advantages and prospects of these concepts for future analysis applications.
引用
收藏
页码:22 / 40
页数:19
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