Spiral breakup in an array of coupled cells: The role of the intercellular conductance

被引:61
作者
Panfilov, AV [1 ]
机构
[1] Univ Utrecht, Dept Theoret Biol, NL-3584 CH Utrecht, Netherlands
关键词
D O I
10.1103/PhysRevLett.88.118101
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We study numerically how the intercellular conductance affects the process of spiral breakup in an array of coupled excitable cells. The cell dynamics are described by the Aliev-Panlov model, and the intercellular connection is made via Ohmic elements. We find that decreasing intercellular conductance can prevent the breaking up of a spiral wave into a complex spatiotemporal pattern. We study the mechanism of this effect and show that the breakup disappears because of increasing the diastolic interval of an initial spiral wave.
引用
收藏
页码:4 / 118101
页数:4
相关论文
共 27 条
[1]   A simple two-variable model of cardiac excitation [J].
Aliev, RR ;
Panfilov, AV .
CHAOS SOLITONS & FRACTALS, 1996, 7 (03) :293-301
[2]   CIRCUS MOVEMENT IN RABBIT ATRIAL MUSCLE AS A MECHANISM OF TACHYCARDIA [J].
ALLESSIE, MA ;
BONKE, FIM ;
SCHOPMAN, FJ .
CIRCULATION RESEARCH, 1973, 33 (01) :54-62
[3]   Alternative scenarios of spiral breakup in a reaction-diffusion model with excitable and oscillatory dynamics [J].
Bär, M ;
Or-Guil, M .
PHYSICAL REVIEW LETTERS, 1999, 82 (06) :1160-1163
[4]   EUCLIDEAN SYMMETRY AND THE DYNAMICS OF ROTATING SPIRAL WAVES [J].
BARKLEY, D .
PHYSICAL REVIEW LETTERS, 1994, 72 (01) :164-167
[5]   Spiral waves in two-dimensional models of ventricular muscle: Formation of a stationary core [J].
Beaumont, J ;
Davidenko, N ;
Davidenko, JM ;
Jalife, J .
BIOPHYSICAL JOURNAL, 1998, 75 (01) :1-14
[6]   INSTABILITIES OF A PROPAGATING PULSE IN A RING OF EXCITABLE MEDIA [J].
COURTEMANCHE, M ;
GLASS, L ;
KEENER, JP .
PHYSICAL REVIEW LETTERS, 1993, 70 (14) :2182-2185
[7]   RE-ENTRANT ROTATING WAVES IN A BEELER-REUTER BASED MODEL OF TWO-DIMENSIONAL CARDIAC ELECTRICAL ACTIVITY [J].
Courtemanche, Marc ;
Winfree, Arthur T. .
INTERNATIONAL JOURNAL OF BIFURCATION AND CHAOS, 1991, 1 (02) :431-444
[8]   Preventing ventricular fibrillation by flattening cardiac restitution [J].
Garfinkel, A ;
Kim, YH ;
Voroshilovsky, O ;
Qu, ZL ;
Kil, JR ;
Lee, MH ;
Karagueuzian, HS ;
Weiss, JN ;
Chen, PS .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (11) :6061-6066
[9]  
Guevara M. R., 1984, Computers in Cardiology (Cat. No. 84CH2078-4), P167
[10]   SPIRAL BREAKUP IN A NEW MODEL OF DISCRETE EXCITABLE MEDIA [J].
ITO, H ;
GLASS, L .
PHYSICAL REVIEW LETTERS, 1991, 66 (05) :671-674