Flavonoids: Old and new aspects of a class of natural therapeutic drugs

被引:1015
作者
Di Carlo, G
Mascolo, N
Izzo, AA
Capasso, F
机构
[1] Univ Naples Federico II, Dept Expt Pharmacol, I-80131 Naples, Italy
[2] Univ Salerno, Dept Pharmaceut Sci, I-84084 Salerno, Italy
关键词
flavonoids; enzyme activity; antihepatotoxic activity; antiallergic activity; and-inflammatory activity; antiosteoporotic activity; antitumor activity;
D O I
10.1016/S0024-3205(99)00120-4
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Flavonoids are natural products widely distributed in the vegetable kingdom and currently consumed in large amounts in the daily diet. Flavonoids are capable of modulating the activity of enzymes and affect the behaviour of many cell systems, suggesting that the compounds may possess significant antihepatotoxic, antiallergic, anti-inflammatory, antiosteoporotic and even antitumor activities. This review summarizes available data on these beneficial effects of flavonoids.
引用
收藏
页码:337 / 353
页数:17
相关论文
共 104 条
  • [101] DERMAL INTOXICATION OF MICE WITH BIS(2-CHLOROETHYL)SULPHIDE AND THE PROTECTIVE EFFECT OF FLAVONOIDS
    VIJAYARAGHAVAN, R
    SUGENDRAN, K
    PANT, SC
    HUSAIN, K
    MALHOTRA, RC
    [J]. TOXICOLOGY, 1991, 69 (01) : 35 - 42
  • [102] ANTI-INFLAMMATORY AND ANTI-ULCER PROPERTIES OF HYPOLAETIN-8-GLUCOSIDE, A NOVEL PLANT FLAVONOID
    VILLAR, A
    GASCO, MA
    ALCARAZ, MJ
    [J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1984, 36 (12) : 820 - 823
  • [103] EFFECT OF IPRIFLAVONE ON GLUCOCORTICOID-INDUCED OSTEOPOROSIS IN RATS
    YAMAZAKI, I
    SHINO, A
    SHIMIZU, Y
    TSUKUDA, R
    SHIRAKAWA, Y
    KINOSHITA, M
    [J]. LIFE SCIENCES, 1986, 38 (10) : 951 - 958
  • [104] INDUCTION OF THE NODA PROMOTER OF RHIZOBIUM-LEGUMINOSARUM SYM PLASMID PRL1JI BY PLANT FLAVANONES AND FLAVONES
    ZAAT, SAJ
    WIJFFELMAN, CA
    SPAINK, HP
    VANBRUSSEL, AAN
    OKKER, RJH
    LUGTENBERG, BJJ
    [J]. JOURNAL OF BACTERIOLOGY, 1987, 169 (01) : 198 - 204