Cloning and expression of medaka Dachshund

被引：13

作者：

Loosli, F

Mardon, G

Wittbrodt, J

机构：

[1] European Mol Biol Lab, Dev Biol Programme, D-69117 Heidelberg, Germany

[2] Baylor Coll Med, Dept Pathol, Program Dev Biol, Houston, TX 77030 USA

[3] Baylor Coll Med, Dept Mol & Human Genet, Program Dev Biol, Houston, TX 77030 USA

[4] Baylor Coll Med, Dept Neurosci, Program Dev Biol, Houston, TX 77030 USA

[5] Baylor Coll Med, Dept Ophthalmol, Program Dev Biol, Houston, TX 77030 USA

来源：

MECHANISMS OF DEVELOPMENT | 2002年 / 112卷 / 1-2期

关键词：

dachshund; teleost; medaka eye; sensory placodes; somite; finbud;

D O I：

10.1016/S0925-4773(01)00649-9

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The nuclear factor dachshund (dac) is a regulator of retinal cell fate determination in Drosophila. We have cloned a Dachshund homologue of a lower vertebrate, the teleost medaka (Oryzias latipes). Sequence comparison reveals high similarity of medaka Dachshund (OlDach) to the known homologues in higher vertebrates and Drosophila. OlDach is first expressed at early somitogenesis stages in the otic placode territory and forming somites. Subsequently, expression is detected in the retina, specific regions of the central nervous system, pancreas and the finbuds. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：203 / 206

页数：4

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