Cognitive-behavioral stress management decreases dysphoric mood and herpes simplex virus-type 2 antibody titers in symptomatic HIV-seropositive gay men

被引：93

作者：

Lutgendorf, SK

Antoni, MH

Ironson, G

Klimas, N

Kumar, M

Starr, K

McCabe, P

Cleven, K

Fletcher, MA

Schneiderman, N

机构：

[1] UNIV MIAMI,DEPT PSYCHOL,CORAL GABLES,FL 33124

[2] UNIV MIAMI,DEPT PSYCHIAT,CORAL GABLES,FL 33124

[3] UNIV MIAMI,DEPT MED,CORAL GABLES,FL 33124

[4] VET ADM CTR,MIAMI,FL

来源：

JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY | 1997年 / 65卷 / 01期

关键词：

D O I：

10.1037/0022-006X.65.1.31

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

This study tested the effects of a 10-week group cognitive-behavioral stress management (CBSM) intervention on mood and immunologic parameters in HIV-seropositive gay men whose disease had progressed to a symptomatic stage. Men were randomized to tither CBSM or a modified waiting list control group. The CBSM intervention significantly decreased self-reported dysphoria, anxiety, and total distress. Individuals who practiced relaxation more consistently had significantly greater drops in dysphoria. The intervention also decreased herpes simplex virus-Type 2 (HSV-2) immunoglobulin G antibody titers. The control group showed no significant changes in either mood or antibody titers. Individual difference analyses revealed that decreases in dysphoria significantly predicted lower HSV-2 antibody titers by the end of the 10-week period. Neither group displayed changes in HSV-Type 1 antibody titers or in CD4+ or CD8+ cell numbers.

引用

页码：31 / 43

页数：13

共 73 条

[1] THE HERPES-SIMPLEX VIRUS IMMEDIATE-EARLY PROTEIN, ICP4, IS REQUIRED TO POTENTIATE REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS IN CD4+ LYMPHOCYTES [J].