Design of antineoplastic agents on the basis of the ''2-phenylnaphthalene-type'' structural pattern .3. Synthesis and biological activity evaluation of 5H-benzo[b]naphtho[2,3-d]pyrrole-6,11-dione derivatives

被引:51
作者
Luo, YL
Chou, TC
Cheng, CC
机构
[1] UNIV KANSAS,MED CTR,DEPT PHARMACOL TOXICOL & THERAPEUT,KANSAS CITY,KS 66160
[2] MEM SLOAN KETTERING CANC CTR,BIOCHEM PHARMACOL LAB,NEW YORK,NY 10021
关键词
D O I
10.1002/jhet.5570330120
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A number of 5H-Benzo[b]naphtho[2,3-d]pyrrole-6,11-dione derivatives were synthesized. Their biological activity was compared with that of the corresponding benzoxazolo- and benzthiazolo-analogues.
引用
收藏
页码:113 / 117
页数:5
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