A polysaccharide isolated from the medicinal herb Bletilla striata induces endothelial cells proliferation and vascular endothelial growth factor expression in vitro

被引：189

作者：

Wang, CM

Sun, JT

Luo, Y

Xue, WH

Diao, HJ

Dong, L

Chen, JN

Zhang, JF ^{[1
]}

机构：

[1] Nanjing Univ, Sch Life Sci, State Key Lab Pharmaceut Biotechnol, Nanjing 210008, Peoples R China

[2] Nanjing Univ, Sch Med, Affiliated Gulou Hosp, Dept Neurosurg, Nanjing 210008, Peoples R China

来源：

BIOTECHNOLOGY LETTERS | 2006年 / 28卷 / 08期

基金：

中国国家自然科学基金;

关键词：

Bletilla striata; cell proliferation; endothelial cells; polysaccharides; vascular endothelial growth factor;

D O I：

10.1007/s10529-006-0011-x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

A polysaccharide from the traditional Chinese medicinal herb, Bletilla striata (Thunb.) Reichb. f., was isolated, purified and characterized. It induced the proliferation of human umbilical vascular endothelial cells and the expression of vascular endothelial growth factor up to 156% and 147% of control after 72 h, respectively.

引用

收藏

页码：539 / 543

页数：5

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