Polarity and Differential Inheritance-Universal Attributes of Life?

被引:98
作者
Macara, Ian G. [1 ]
Mili, Stavroula [1 ]
机构
[1] Univ Virginia, Sch Med, Ctr Cell Signaling, Dept Microbiol, Charlottesville, VA 22908 USA
关键词
D O I
10.1016/j.cell.2008.11.006
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
When and why did cell polarization arise? Recent work in bacteria and yeast suggests that polarization may have evolved to restrict senescence to one daughter during division by enabling the differential segregation of damaged material. In more complex organisms, polarity functions have diversified to permit the differential inheritance of centrosomes, RNAs, proteins, and membranes, which is essential for the generation of diverse cell types from stem cells and for morphogenesis.
引用
收藏
页码:801 / 812
页数:12
相关论文
共 95 条
  • [71] Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex
    Pereira, G
    Tanaka, TU
    Nasmyth, K
    Schiebel, E
    [J]. EMBO JOURNAL, 2001, 20 (22) : 6359 - 6370
  • [72] Potten CS, 2002, J CELL SCI, V115, P2381
  • [73] Functionally unequal centrosomes drive spindle orientation in asymmetrically dividing Drosophila neural stem cells
    Rebollo, Elena
    Sampaio, Paula
    Januschke, Jens
    Llamazares, Salud
    Varmark, Hanne
    Gonzalez, Cayetano
    [J]. DEVELOPMENTAL CELL, 2007, 12 (03) : 467 - 474
  • [74] Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes
    Rujano, Maria A.
    Bosveld, Floris
    Salomons, Florian A.
    Dijk, Freark
    van Waarde, Maria A. W. H.
    van der Want, Johannes J. L.
    de Vos, Rob A. I.
    Brunt, Ewout R.
    Sibon, Ody C. M.
    Kampinga, Harm H.
    [J]. PLOS BIOLOGY, 2006, 4 (12) : 2325 - 2335
  • [75] A role for a novel centrosome cycle in asymmetric cell division
    Rusan, Nasser M.
    Peifer, Mark
    [J]. JOURNAL OF CELL BIOLOGY, 2007, 177 (01) : 13 - 20
  • [76] Bmi1 is expressed in vivo in intestinal stem cells
    Sangiorgi, Eugenio
    Capecchi, Mario R.
    [J]. NATURE GENETICS, 2008, 40 (07) : 915 - 920
  • [77] Coordination of endoplasmic reticulum and mRNA localization to the yeast bud
    Schmid, Maria
    Jaedicke, Andreas
    Du, Tung-Gia
    Jansen, Ralf-Peter
    [J]. CURRENT BIOLOGY, 2006, 16 (15) : 1538 - 1543
  • [78] A mechanism for asymmetric segregation of age during yeast budding
    Shcheprova, Zhanna
    Baldi, Sandro
    Frei, Stephanie Buvelot
    Gonnet, Gaston
    Barral, Yves
    [J]. NATURE, 2008, 454 (7205) : 728 - U64
  • [79] Miranda is required for the asymmetric localization of Prospero during mitosis in Drosophila
    Shen, CP
    Jan, LY
    Jan, YN
    [J]. CELL, 1997, 90 (03) : 449 - 458
  • [80] Widespread cytoplasmic mRNA transport in yeast: Identification of 22 bud-localized transcripts using DNA microarray analysis
    Shepard, KA
    Gerber, AP
    Jambhekar, A
    Takizawa, PA
    Brown, PO
    Herschlag, D
    DeRisi, JL
    Vale, RD
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (20) : 11429 - 11434