Iron-catalyzed C-C bond formation by direct functionalization of C-H bonds adjacent to heteroatoms

被引：281

作者：

Li, Zhiping ^{[1
]}

Yu, Rong ^{[1
]}

Li, Haijun ^{[1
]}

机构：

[1] Renmin Univ China, Dept Chem, Beijing 100872, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 39期

关键词：

C-H activation; cross-coupling; heterocycles; iron; peroxides;

D O I：

10.1002/anie.200802215

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Iron/oxidant can do: Heteroatom-containing molecules are abundant in natural products, pharmaceuticals, and materials. It is highly desirable to synthesize these molecules and their derivatives by direct C-H functionalization. The novel title reaction provides a simple and efficient method to construct such molecules by using 1,3-dicarbonyl compounds (see scheme). (Chemical Equation Presented). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7497 / 7500

页数：4

共 77 条

[1] Iron-catalyzed nucleophilic substitution of allylic acetate [J].

Akermark, Bjorn ;

Sjogren, Magnus P. T. .

ADVANCED SYNTHESIS & CATALYSIS, 2007, 349 (17-18) :2641-2646

[2] Asymmetric radical addition of ethers to enantiopure N-p-toluenesulfinyl aldimines, mediated by dimethylzinc-air [J].

Akindele, Tito ;

Yamamoto, Yasutomo ;

Maekawa, Masaru ;

Umeki, Hiroyuki ;

Yamada, Ken-ichi ;

Tomioka, Kiyoshi .

ORGANIC LETTERS, 2006, 8 (25) :5729-5732

[3]

[Anonymous], 2005, ANGEW CHEM

[4] THE SELECTIVE FUNCTIONALIZATION OF SATURATED-HYDROCARBONS - GIF CHEMISTRY [J].

BARTON, DHR ;

DOLLER, D .

ACCOUNTS OF CHEMICAL RESEARCH, 1992, 25 (11) :504-512

[5]

Bergman RG, 2007, NATURE, V446, P391, DOI 10.1038/446391a

[6] An iron-containing ionic liquid as recyclable catalyst for aryl grignard cross-coupling of alkyl halides [J].

Bica, K ;

Gaertner, P .

ORGANIC LETTERS, 2006, 8 (04) :733-735

[7]

Bistri O., 2008, Angew. Chem., V47, P596, DOI [10.1002/ange.200704018, DOI 10.1002/ANGE.200704018]

[8] Iron-catalyzed C-O cross-couplings of phenols with aryl iodides [J].

Bistri, Olivia ;

Correa, Arkaitz ;

Bolm, Carsten .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (03) :586-588

[9] Iron-catalyzed reactions in organic synthesis [J].

Bolm, C ;

Legros, J ;

Le Paih, J ;

Zani, L .

CHEMICAL REVIEWS, 2004, 104 (12) :6217-6254

[10] Ru3(CO)12-catalyzed coupling reaction of sp3 C-H bonds adjacent to a nitrogen atom in alkylamines with alkenes [J].

Chatani, N ;

Asaumi, T ;

Yorimitsu, S ;

Ikeda, T ;

Kakiuchi, F ;

Murai, S .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (44) :10935-10941

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