CML blast crisis resulting in biliary obstruction following BMT

被引：7

作者：

Fleming, DR ^{[1
]}

Slone, SP ^{[1
]}

机构：

[1] UNIV LOUISVILLE,DEPT PATHOL,LOUISVILLE,KY 40202

来源：

BONE MARROW TRANSPLANTATION | 1997年 / 19卷 / 08期

关键词：

chronic myelogenous leukemia; bone marrow transplantation; cholestasis; granulocytic sarcoma;

D O I：

10.1038/sj.bmt.1700748

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Allogeneic BMT is the treatment of choice for various hematologic malignancies, Despite careful patient scrutiny, a large number of patients experience significant morbidity and mortality due to procedure-related toxicity, Hepatobiliary toxicity presenting as biliary cholestasis, due to the preparative regimen (ie venoocclusive disease), supportive pharmaceuticals, and/or GVHD have been implicated, We report a unique cause of cholestasis in a patient undergoing BMT for CML, The cholestasis was found to be secondary to relapsed leukemia, which resulted in a granulocytic sarcoma obstructing the biliary ductal system.

引用

页码：853 / 854

页数：2