From Mutation Identification to Therapy: Discovery and Origins of the First Approved Gene Therapy in the Western World

被引：29

作者：

Kastelein, John J. P. ^{[1
]}

Ross, Colin J. D. ^{[2
,3
,4
]}

Hayden, Michael R. ^{[3
,4
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands

[2] Univ British Columbia, Dept Pediat, Vancouver, BC V5Z 4H4, Canada

[3] Univ British Columbia, Ctr Mol Med & Therapeut, Child & Family Res Inst, Vancouver, BC V5Z 4H4, Canada

[4] Univ British Columbia, Dept Med Genet, Vancouver, BC V5Z 4H4, Canada

来源：

HUMAN GENE THERAPY | 2013年 / 24卷 / 05期

关键词：

LIPOPROTEIN-LIPASE GENE; CORONARY-ARTERY-DISEASE; LPLS447X BENEFICIAL MUTATION; FRENCH-CANADIAN POPULATION; HDL CHOLESTEROL LEVELS; GUINEA-PIG HEARTS; FAMILIAL HYPERCHOLESTEROLEMIA; CAUSES CHYLOMICRONEMIA; PLASMA-LIPOPROTEINS; DEFICIENT PATIENTS;

D O I：

10.1089/hum.2013.063

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：472 / 478

页数：7

共 64 条

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