Activated alumina as an energy source for peptide bond formation:: Consequences for mineral-mediated prebiotic processes

被引:40
作者
Bujdák, J
Rode, BM
机构
[1] Slovak Acad Sci, Inst Inorgan Chem, Bratislava 84236, Slovakia
[2] Univ Innsbruck, Inst Gen Inorgan & Theoret Chem, A-6020 Innsbruck, Austria
关键词
amino acids; alumina; alanine; catalysis; clay; peptide bond formation; prebiotic;
D O I
10.1007/s007260170014
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The catalytic properties of various forms of alumina were tested for alanine dimerization reaction. The catalytic efficiency of alumina depends on the structure, as well as on acid/base properties of the catalyst. The highest yields of Ala(2) were achieved on activated alumina with surface of neutral pH (about 3% conversion after 2 weeks). Thermal analysis of Ala + alumina reaction systems shows that the thermal behavior of amino acid changes substantially in contact with the activated surface of the alumina catalyst. The reaction of Ala is detected as being strongly endothermic by differential thermal analysis of pure amino acid (above 250 degreesC). The alanine endothermic reaction is shifted substantially to lower values (below 200 degreesC) and hardly detectable if activated alumina is present. The reaction mechanism of amino acid activation on alumina surface and its significance for mineral-catalyzed prebiotic peptide bond formation are discussed.
引用
收藏
页码:281 / 291
页数:11
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