Electrophoretic behaviour of zwitterionic compounds in capillary electrophoresis -: Prediction of mobility of several quinolones

被引：26

作者：

Barrón, D ^{[1
]}

Jiménez-Lozano, E ^{[1
]}

Barbosa, J ^{[1
]}

机构：

[1] Univ Barcelona, Dept Analyt Chem, E-08028 Barcelona, Spain

来源：

ANALYTICA CHIMICA ACTA | 2000年 / 415卷 / 1-2期

关键词：

capillary electrophoresis; quinolones; zwitterions;

D O I：

10.1016/S0003-2670(00)00884-9

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A model of electrophoretic behaviour is studied in order to optimize the separation of zwitterionic substances by capillary electrophoresis. The equations derived allow the electrophoretic mobilities of substances at each pH to be predicted and, consequently the resolution between pairs of substances. The model considers the effect of ionic strength and can be applied to zwitterionic substances with very dose pK(a) values. The model is tested to obtain the optimum pH values for the separation of a series of eight quinolones on the basis of a few initial experiments. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：83 / 93

页数：11

共 31 条

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