Circulating tumour-derived nucleic acids in cancer patients: potential applications as tumour markers

被引：51

作者：

Chan, K. C. A.

Lo, Y. M. D.

机构：

[1] Chinese Univ Hong Kong, Dept Chem Pathol, Prince Wales Hosp, Shatin, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Li Ka Shing Inst Hlth Sci, Prince Wales Hosp, Shatin, Hong Kong, Peoples R China

[3] Chinese Univ Hong Kong, State Key Lab Oncol S China, Prince Wales Hosp, Shatin, Hong Kong, Peoples R China

来源：

BRITISH JOURNAL OF CANCER | 2007年 / 96卷 / 05期

关键词：

tumour marker; plasma/serum DNA; plasma/serum RNA; circulating nucleic acids;

D O I：

10.1038/sj.bjc.6603625

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Tumour-associated changes have been observed in the circulating nucleic acids of cancer patients and have been proposed to be useful for the detection and monitoring of cancers. In this review, different approaches for detecting tumour-associated nucleic acids in the circulation and their potential applications as tumour markers are discussed.

引用

页码：681 / 685

页数：5

共 29 条

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