SERRS immunoassay for quantitative human CRP analysis

被引：30

作者：

Campbell, Fiona M. ^{[1
]}

Ingram, Andrew ^{[2
]}

Monaghan, Paul ^{[3
]}

Cooper, Jon ^{[3
]}

Sattar, Naveed ^{[4
]}

Eckersall, P. David ^{[1
]}

Graham, Duncan ^{[2
]}

机构：

[1] Univ Glasgow, Fac Vet Med, Inst Comparat Med, Div Anim Prod & Publ Hlth, Glasgow G61 1QH, Lanark, Scotland

[2] Univ Strathclyde, Dept Pure & Appl Chem, WestCHEM, Ctr Mol Nanometrol, Glasgow G1 1XL, Lanark, Scotland

[3] Univ Glasgow, Dept Elect & Elect Engn, Glasgow G12 8LT, Lanark, Scotland

[4] Royal Infirm, Dept Vasc Biochem, Glasgow G4 0SF, Lanark, Scotland

来源：

ANALYST | 2008年 / 133卷 / 10期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1039/b808087a

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

SERRS has been used for the first time for the measurement of C-reactive protein (CRP) in an immunoassay. CRP, a biological marker for the diagnosis of infection and inflammation, is quantified in an ELISA using conventional reagents, but the usual colorimetric detection step is replaced by SERRS detection, offering improved sensitivity and potential for multiplexing analysis.

引用

页码：1355 / 1357

页数：3

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