brain stimulation;
neuromodulation;
developmental disorders;
autism;
Williams syndrome;
schizophrenia;
social cognition;
TRANSCRANIAL MAGNETIC STIMULATION;
AUTISM SPECTRUM DISORDER;
RIGHT TEMPOROPARIETAL JUNCTION;
WILLIAMS-SYNDROME;
NEURODEVELOPMENTAL DISORDERS;
CORTICOSPINAL EXCITABILITY;
FUNCTIONAL CONNECTIVITY;
NEGATIVE SYMPTOMS;
SCHIZOPHRENIA;
RTMS;
D O I:
10.3389/fnins.2015.00294
中图分类号:
Q189 [神经科学];
学科分类号:
071006 [神经生物学];
摘要:
Being socially connected directly impacts our basic needs and survival. People with deficits in social cognition might exhibit abnormal behaviors and face many challenges in our highly social-dependent world. These challenges and limitations are associated with a substantial economical and subjective impact. As many conditions where social cognition is affected are highly prevalent, more treatments have to be developed. Based on recent research, we review studies where non-invasive neuromodulatory techniques have been used to promote Social Plasticity in developmental disorders. We focused on three populations where non-invasive brain stimulation seems to be a promising approach in inducing social plasticity: Schizophrenia, Autism Spectrum Disorder (ASD) and Williams Syndrome (WS). There are still very few studies directly evaluating the effects of transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) in the social cognition of these populations. However, when considering the promising preliminary evidences presented in this review and the limited amount of clinical interventions available for treating social cognition deficits in these populations today, it is clear that the social neuroscientist arsenal may profit from non-invasive brain stimulation techniques for rehabilitation and promotion of social plasticity.
机构:
Univ Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Univ Sao Paulo, SIN, Sao Paulo, Brazil
Univ Sao Paulo, CINA, Sao Paulo, Brazil
Univ Sao Paulo, Inst Psychiat, Lab Neurosci LIM 27, Sao Paulo, BrazilUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Brunoni, Andre R.
;
Shiozawa, Pedro
论文数: 0引用数: 0
h-index: 0
机构:
Santa Casa Med Sch, Lab Clin Neuromodulat, Sao Paulo, BrazilUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Shiozawa, Pedro
;
Truong, Dennis
论文数: 0引用数: 0
h-index: 0
机构:
CUNY, CCNY, Dept Biomed Engn, New York, NY USAUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Truong, Dennis
;
Javitt, Daniel C.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Coll Phys & Surg, Div Expt Therapeut, Dept Psychiat, New York, NY USAUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Javitt, Daniel C.
;
Elkis, Helio
论文数: 0引用数: 0
h-index: 0
机构:
Univ Sao Paulo, Dept & Inst Psychiat, Sao Paulo, BrazilUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Elkis, Helio
;
论文数: 引用数:
h-index:
机构:
Fregni, Felipe
;
Bikson, Marom
论文数: 0引用数: 0
h-index: 0
机构:
CUNY, CCNY, Dept Biomed Engn, New York, NY USAUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
机构:
Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
Harvard Univ, Sch Med, Massachusetts Gen Hosp, Boston, MA 02114 USA
Univ Sao Paulo, Inst Psychol, Dept Neurosci & Behav, Sao Paulo, Brazil
Univ Sao Paulo, Univ Hosp, Ctr Pesquisas Clin, Sao Paulo, BrazilHarvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
Brunoni, Andre Russowsky
;
Amadera, Joao
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
Harvard Univ, Sch Med, Massachusetts Gen Hosp, Boston, MA 02114 USAHarvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
Amadera, Joao
;
Berbel, Bruna
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
Harvard Univ, Sch Med, Massachusetts Gen Hosp, Boston, MA 02114 USAHarvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
机构:
Univ Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Univ Sao Paulo, SIN, Sao Paulo, Brazil
Univ Sao Paulo, CINA, Sao Paulo, Brazil
Univ Sao Paulo, Inst Psychiat, Lab Neurosci LIM 27, Sao Paulo, BrazilUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Brunoni, Andre R.
;
Shiozawa, Pedro
论文数: 0引用数: 0
h-index: 0
机构:
Santa Casa Med Sch, Lab Clin Neuromodulat, Sao Paulo, BrazilUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Shiozawa, Pedro
;
Truong, Dennis
论文数: 0引用数: 0
h-index: 0
机构:
CUNY, CCNY, Dept Biomed Engn, New York, NY USAUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Truong, Dennis
;
Javitt, Daniel C.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Coll Phys & Surg, Div Expt Therapeut, Dept Psychiat, New York, NY USAUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Javitt, Daniel C.
;
Elkis, Helio
论文数: 0引用数: 0
h-index: 0
机构:
Univ Sao Paulo, Dept & Inst Psychiat, Sao Paulo, BrazilUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
Elkis, Helio
;
论文数: 引用数:
h-index:
机构:
Fregni, Felipe
;
Bikson, Marom
论文数: 0引用数: 0
h-index: 0
机构:
CUNY, CCNY, Dept Biomed Engn, New York, NY USAUniv Sao Paulo, Dept & Inst Psychiat, Sao Paulo, Brazil
机构:
Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
Harvard Univ, Sch Med, Massachusetts Gen Hosp, Boston, MA 02114 USA
Univ Sao Paulo, Inst Psychol, Dept Neurosci & Behav, Sao Paulo, Brazil
Univ Sao Paulo, Univ Hosp, Ctr Pesquisas Clin, Sao Paulo, BrazilHarvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
Brunoni, Andre Russowsky
;
Amadera, Joao
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
Harvard Univ, Sch Med, Massachusetts Gen Hosp, Boston, MA 02114 USAHarvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
Amadera, Joao
;
Berbel, Bruna
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA
Harvard Univ, Sch Med, Massachusetts Gen Hosp, Boston, MA 02114 USAHarvard Univ, Sch Med, Spaulding Rehabil Hosp, Dept Phys Med & Rehabil,Lab Neuromodulat, Boston, MA 02114 USA