Anthracylmethyl crown ethers as fluorescence sensors of saxitoxin

被引:20
作者
Gawley, RE
Zhang, QH
Higgs, PI
Wang, SP
Leblanc, RM [1 ]
机构
[1] Univ Miami, Dept Chem, Coral Gables, FL 33124 USA
[2] Univ Miami, NIEHS, Marine & Freshwater Biomed Sci Ctr, Coral Gables, FL 33124 USA
关键词
D O I
10.1016/S0040-4039(99)01066-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Anthracylmethyl crowns 1 and 2 show up to 30-fold increase in fluorescence emission intensity in the presence of saxitoxin in ethanol, and sixfold enhancement in 80% ethanol. The binding constant between saxitoxin and 1 is 3880 M-1 in ethanol and 1100 M-1 in 80% ethanol. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:5461 / 5465
页数:5
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1973, NEW ENGL J MED, V288, P1126