Lipid-coated enzymes as efficient catalysts in organic media

被引：73

作者：

Okahata, Y

Mori, T

机构：

[1] Dept. of Biomolecular Engineering, Tokyo Institute of Technology, Nagatsuda, Midori-ku, Yokohama 226, Japan

来源：

TRENDS IN BIOTECHNOLOGY | 1997年 / 15卷 / 02期

关键词：

D O I：

10.1016/S0167-7799(97)84203-5

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new way of solubilizing hydrolytic enzymes so that they can be used in organic solvents is to coat them with lipid monolayers, Lipid-coated enzymes have been used successfully for a number of different types of reactions in organic media or organic-aqueous, two-phase systems; for example, enantioselective esterification by lipase, transphosphatidylation of water-insoluble phospholipids by phospholipase D, hydrolysis of a lipophilic substrate by a catalytic antibody and transglycosylation by beta-D-galactosidase.

引用

页码：50 / 54

页数：5

共 32 条

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BENKOVIC SJ, 1992, ANNU REV BIOCHEM, V61, P29

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