Direct Electrochemistry of Hemoglobin and Its Electrocatalysis Based on Hyaluronic Acid and Room Temperature Ionic Liquid

被引：41

作者：

Gao, Ruifang ^{[1
]}

Shangguan, Xiaodong ^{[1
]}

Qiao, Guangjun ^{[1
]}

Zheng, Jianbin ^{[1
]}

机构：

[1] NW Univ Xian, Shaanxi Prov Key Lab Electroanalyt Chem, Inst Analyt Sci, Xian 710069, Shaanxi, Peoples R China

来源：

ELECTROANALYSIS | 2008年 / 20卷 / 23期

基金：

中国国家自然科学基金;

关键词：

Electroanalysis; Direct electrochemistry; Homoglobin; Room temperature ionic liquids; Hyaluronic acid;

D O I：

10.1002/elan.200804353

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A biocomposite material of hyaluronic acid (HA) and room temperature ionic liquid, 1-butyl-3-methyl-imidazolium tetrafluoroborate (BMIMBF4) was fabricated and characterized by voltammetry and electrochemical impedance spectroscopy. Hemoglobin (Hb), as a model protein, was immobilized in this biocomposite on glassy carbon electrode to investigate its direct electrochemistry A pair of well-defined, quasireversible cyclic voltammetric peaks appeared with the formal potentials (E-o1) at -0.360V (vs. SCE). The Hb modified electrode exhibited an excellent electrocatalytic activity to the reduction of H2O2, with a wide linear range, good selectivity, sensitivity and reproducibility, which had potential application to fabrication the third-generation biosensor.

引用

页码：2537 / 2542

页数：6

共 41 条

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