Structural elucidation and bioactivity of novel secondary metabolites from Carex distachya

被引：18

作者：

Fiorentino, A ^{[1
]}

D'Abrosca, B ^{[1
]}

Izzo, A ^{[1
]}

Pacifico, S ^{[1
]}

Monaco, P ^{[1
]}

机构：

[1] Univ Naples 2, Dipartimento Sci Vita, I-81100 Caserta, Italy

来源：

TETRAHEDRON | 2006年 / 62卷 / 14期

关键词：

Carex distachya Desf; carexanes; prenyl stilbenes; NMR analysis; phytotoxicity; Lactuca sativa;

D O I：

10.1016/j.tet.2006.01.066

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

Four new carexanes and a new seco-derivative metabolite have been isolated and characterized from the herbaceous plant Carex distachya Desf. All of the structures have been elucidated on the basis of spectroscopic data. These compounds derive from the cyclization of prenylate stylbenoid precursors. The seco-carexane is formed by a further oxidative cleavage of the C-7-C-8 bond. The absolute configurations have been determined by Mosher's method using appropriate chemical correlations. All of the carexanes A-H have been tested for their phytotoxicity against Lactuca sativa. The bioassays showed an inhibitory effect on seed germination for all compounds described in this report. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3259 / 3265

页数：7

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