Antidiabetic principles of natural medicines.: V. Aldose reductase inhibitors from Myrcia multiflora DC. (2):: Structures of myrciacitrins III, IV, and V

被引:68
作者
Matsuda, H [1 ]
Nishida, N [1 ]
Yoshikawa, M [1 ]
机构
[1] Kyoto Pharmaceut Univ, Yamashima Ku, Kyoto 607, Japan
关键词
myrciacitrin; Myrcia multiflora; aldose reductase inhibitor; flavanone glucoside; acylated flavanone glucoside;
D O I
10.1248/cpb.50.429
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Following the characterization of myrciacitrins I and II and myreiaphenones A and B, three,new flavanone glucosides, myrciacitrins III, IV, and V, were isolated from the leaves of Brazilian Myrcia multiflora. The structures of new myrciacitrins were elucidated on the basis of physicochemical and chemical evidence. Myrciacitrins were found to show potent inhibitory activity on aldose reductase.
引用
收藏
页码:429 / 431
页数:3
相关论文
共 8 条
[2]  
Matsuda H, 1999, CHEM PHARM BULL, V47, P1725, DOI 10.1248/cpb.47.1725
[3]  
Matsuda H, 2001, HETEROCYCLES, V55, P1499
[4]   Flavonol glycosides and steroidal saponins from the leaves of Cestrum nocturnum and their cytotoxicity [J].
Mimaki, Y ;
Watanabe, K ;
Ando, Y ;
Sakuma, C ;
Sashida, Y ;
Furuya, S ;
Sakagami, H .
JOURNAL OF NATURAL PRODUCTS, 2001, 64 (01) :17-22
[5]  
TERASHIMA H, 1984, J PHARMACOL EXP THER, V229, P226
[6]   Polyphenol constituents from Salacia species:: Quantitative analysis of mangiferin with α-glucosidase and aldose reductase inhibitory activities [J].
Yoshikawa, M ;
Nishida, N ;
Shimoda, H ;
Takada, M ;
Kawahara, Y ;
Matsuda, H .
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2001, 121 (05) :371-378
[7]   Medicinal flowers.: III.: Marigold.: (1):: Hypoglycemic, gastric emptying inhibitory, and gastroprotective principles and new oleanane-type triterpene oligoglycosides, calendasaponins A, B, C, and D, from Egyptian Calendula officinalis [J].
Yoshikawa, M ;
Murakami, T ;
Kishi, A ;
Kageura, T ;
Matsuda, H .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2001, 49 (07) :863-870
[8]  
Yoshikawa M, 1998, CHEM PHARM BULL, V46, P113, DOI 10.1248/cpb.46.113