Extending the scope of Ruppert's reagent: trifluoromethylation of imines

被引：59

作者：

Blazejewski, JC ^{[1
]}

Anselmi, E ^{[1
]}

Wilmshurst, MP ^{[1
]}

机构：

[1] Univ Versailles, SIRCOB, CNRS, ESA 8086, F-78035 Versailles, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(99)01004-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The absence of reactivity of imines towards Ruppert's reagent (CF3SiMe3) could be overcome by the addition of an auxiliary silylating agent to the reaction medium. Under these conditions variously substituted alpha-trifluoromethylated amines are readily obtained from the corresponding imines. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：5475 / 5478

页数：4

共 19 条

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