Extremely Tight Binding of a Ruthenium Complex to Glycogen Synthase Kinase 3

被引：48

作者：

Atilla-Gokcumen, G. Ekin ^{[1
]}

Pagano, Nicholas ^{[1
]}

Streu, Craig ^{[2
]}

Maksimoska, Jasna ^{[2
]}

Filippakopoulos, Panagis ^{[3
]}

Knapp, Stefan ^{[3
]}

Meggers, Eric ^{[1
]}

机构：

[1] Univ Marburg, Fachbereich Chem, D-35043 Marburg, Germany

[2] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA

[3] Univ Oxford, Botnar Res Ctr, Ctr Struct Genom, Oxford OX3 7LD, England

来源：

CHEMBIOCHEM | 2008年 / 9卷 / 18期

基金：

美国国家卫生研究院;

关键词：

bioorganometallic chemistry; glycogen synthase kinase 3; inhibitors; picomolar binding constant; ruthenium;

D O I：

10.1002/cbic.200800489

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

[No abstract available]

引用

页码：2933 / 2936

页数：4

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