Actinobacillus pleuropneumoniae:: pathobiology and pathogenesis of infection

被引:311
作者
Bossé, JT
Janson, H
Sheehan, BJ
Beddek, AJ
Rycroft, AN
Kroll, JS
Langford, PR
机构
[1] Univ London Imperial Coll Sci & Technol, Fac Med, Dept Paediat, Mol Infect Dis Grp, London W2 1PG, England
[2] Univ London, Hatfield AL9 7TA, Herts, England
基金
英国惠康基金; 英国生物技术与生命科学研究理事会;
关键词
Actinobacillus pleuropneumoniae; pathogenicity; pathology;
D O I
10.1016/S1286-4579(01)01534-9
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Actinobacillus pleuropneumoniae causes porcine pleuropneumonia. a highly contagious disease for which there is no effective vaccine. This review considers how adhesins, iron-acquisition factors, capsule and lipopolysaccharide, RTX cytotoxins and other potential future vaccine components contribute to colonisation, to avoidance of host clearance mechanisms and to damage of host tissues. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:225 / 235
页数:11
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