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Inhibition of acetylcholinesterase activity by essential oil from Citrus paradisi

被引：68
作者：
Miyazawa, M
Tougo, H
Ishihara, M
机构：
[1] Kinki Univ, Fac Sci & Engn, Dept Appl Chem, Higashiosaka, Osaka 5778502, Japan
[2] Shiono Koryo Co Ltd, Lab Flavor Subst, Osaka 5320033, Japan
来源：
NATURAL PRODUCT LETTERS | 2001年 / 15卷 / 03期
关键词：
acetylcholinesterase; Citrus species; Citrus paradisi; inhibition of enzyme activity; nootkatone; auraptene; synergistic effect;
D O I：
10.1080/10575630108041281
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要：
Inhibition of acetyleholinesterase (AChE) activity by essential oils of Citrus paradisi (grapefruit pink in USA) was studied. Inhibition of AChE was measured by the colorimetric method. Nootkatone and auraptene were isolated from C. paradisi oil and showed 17-24% inhibition of AChE activity at the concentration of 1.62 mug/mL.
引用
收藏
页码：205 / 210
页数：6
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