Adsorption of a blood protein on to hydrophilic sponges based on poly(2-hydroxyethyl methacrylate)

被引：28

作者：

Bajpai, AK ^{[1
]}

Mishra, DD

机构：

[1] Govt Autonomous Sci Coll, Dept Chem, Bose Mem Res Lab, Jabalpur 482001, Madhya Pradesh, India

[2] Shri Ram Inst Technol, Dept Chem, Jabalpur 482002, Madhya Pradesh, India

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 2004年 / 15卷 / 05期

关键词：

D O I：

10.1023/B:JMSM.0000026380.40151.28

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Spongy materials of poly(2-hydroxyethyl methacrylate) were synthesized and the adsorption of bovine serum albumin was carried out onto their surfaces. The sponges were characterized by IR spectral analysis, and water sorption property. It was noticed that the chemical architecture of the sponge has a pronounced impact on both the water sorption capacity and adsorption affinity of the sponge surfaces. The adsorption was also studied kinetically and the effect of pH was also investigated. The synthesized sponges were evaluated for antithrombogenic property by performing blood-clot formation tests. (C) 2004 Kluwer Academic Publishers.

引用

页码：583 / 592

页数：10

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