APPLICATION OF EMPIRICAL MODE DECOMPOSITION (EMD) FOR AUTOMATED DETECTION OF EPILEPSY USING EEG SIGNALS

被引:262
作者
Martis, Roshan Joy [1 ]
Acharya, U. Rajendra [1 ,3 ]
Tan, Jen Hong [1 ]
Petznick, Andrea [4 ]
Yanti, Ratna [1 ]
Chua, Chua Kuang [1 ]
Ng, E. Y. K. [2 ]
Tong, Louis [5 ]
机构
[1] Ngee Ann Polytech, Dept Elect & Comp Engn, Singapore 599489, Singapore
[2] Nanyang Technol Univ, Sch Mech & Aerosp Engn, Singapore 639798, Singapore
[3] Univ Malaya, Fac Engn, Dept Biomed Engn, Kuala Lumpur 59100, Malaysia
[4] Singapore Eye Res Inst, Singapore, Singapore
[5] Singapore Natl Eye Ctr, Singapore, Singapore
关键词
Electroencephalogram (EEG); empirical mode decomposition (EMD); intrinsic mode function (IMF); decision tree; C4.5; PRINCIPAL COMPONENT ANALYSIS; NEURAL NETWORK METHODOLOGY; WAVELET-CHAOS METHODOLOGY; ELECTRICAL-STIMULATION; ALZHEIMERS-DISEASE; SEIZURE DETECTION; IDENTIFICATION; CLASSIFICATION; COMPUTATION; DIAGNOSIS;
D O I
10.1142/S012906571250027X
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
fEpilepsy is a global disease with considerable incidence due to recurrent unprovoked seizures. These seizures can be noninvasively diagnosed using electroencephalogram (EEG), a measure of neuronal electrical activity in brain recorded along scalp. EEG is highly nonlinear, nonstationary and non-Gaussian in nature. Nonlinear adaptive models such as empirical mode decomposition (EMD) provide intuitive understanding of information present in these signals. In this study a novel methodology is proposed to automatically classify EEG of normal, inter-ictal and ictal subjects using EMD decomposition. EEG decomposition using EMD yields few intrinsic mode functions (IMF), which are amplitude and frequency modulated (AM and FM) waves. Hilbert transform of these IMF provides AM and FM frequencies. Features such as spectral peaks, spectral entropy and spectral energy in each IMF are extracted and fed to decision tree classifier for automated diagnosis. In this work, we have compared the performance of classification using two types of decision trees (i) classification and regression tree (CART) and (ii) C4.5. We have obtained the highest average accuracy of 95.33%, average sensitivity of 98%, and average specificity of 97% using C4.5 decision tree classifier. The developed methodology is ready for clinical validation on large databases and can be deployed for mass screening.
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页数:16
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