Recurrence of sarcoidosis following interferon alpha therapy for chronic hepatitis C

被引：55

作者：

Nakajima, M

Kubota, Y

Miyashita, N

Niki, Y

Matsushima, T

Manabe, T

机构：

[1] Department of Internal Medicine, Kawasaki Medical School, Kurashiki

[2] Department of Pathology, Kawasaki Medical School, Kurashiki

[3] Respiratory Division, Department of Internal Medicine, Kawasaki Medical School, Kurashiki 701-01

来源：

INTERNAL MEDICINE | 1996年 / 35卷 / 05期

关键词：

granuloma; IFN-alpha; soluble IL-2;

D O I：

10.2169/internalmedicine.35.376

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a 67-year-old male patient with a known history of sarcoidosis in remission who had recurrent sarcoidosis following a five-month administration of interferon alpha (IFN-alpha) for chronic hepatitis C. He developed bilateral swelling of the parotid glands and bilateral diffuse reticulonodular pulmonary parenchymal opacities on chest roentgenograms. Serum angiotensin converting enzyme (ACE) levels and soluble IL-2 receptor levels were high and a transbronchial lung biopsy revealed noncaseating granulomas. The abnormalities on both laboratory data and chest roentgenograms were resolved after administration of oral prednisolone.

引用

页码：376 / 379

页数：4