Plasminogen activators in vascular remodeling and angiogenesis

被引：46

作者：

Parfyonova, YV ^{[1
]}

Plekhanova, OS ^{[1
]}

Tkachuk, VA ^{[1
]}

机构：

[1] Minist Hlth Russian Federat, Cardiol Res Ctr, Moscow 121552, Russia

来源：

BIOCHEMISTRY-MOSCOW | 2002年 / 67卷 / 01期

关键词：

urokinase; tissue plasminogen activator; cell migration; vascular remodeling; restenosis; angiogenesis;

D O I：

10.1023/A:1013964517211

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review considers cellular and molecular mechanisms of the involvement of plasminogen activators in extracellular proteolysis and cell migration and proliferation. The role of plasminogen activators in vascular remodeling in atherosclerosis, restenosis, and angiogenesis is discussed.

引用

页码：119 / 134

页数：16

共 189 条

[11] INVIVO PATTERNS OF EXPRESSION OF UROKINASE AND ITS INHIBITOR PAI-1 SUGGEST A CONCERTED ROLE IN REGULATING PHYSIOLOGICAL ANGIOGENESIS [J].

BACHARACH, E ;

ITIN, A ;

KESHET, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (22) :10686-10690

[12] Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization [J].

Bajou, K ;

Noël, A ;

Gerard, RD ;

Masson, V ;

Brunner, N ;

Holst-Hansen, C ;

Skobe, M ;

Fusenig, NE ;

Carmeliet, P ;

Collen, D ;

Foidart, JM .

NATURE MEDICINE, 1998, 4 (08) :923-928

[13]

BATTEGAY EJ, 1995, J MOL MED, V73, P333

[14]

BERMAN M, 1982, INVEST OPHTH VIS SCI, V22, P191

[15]

Berse B, 1999, CLIN EXP IMMUNOL, V115, P176

[16] Signal transduction and the u-PA/u-PAR system [J].

Besser, D ;

Verde, P ;

Nagamine, Y ;

Blasi, F .

FIBRINOLYSIS, 1996, 10 (04) :215-237

[17]

Blasi F, 1999, THROMB HAEMOSTASIS, V82, P298

[18] MOUSE OVARIAN GRANULOSA-CELLS PRODUCE UROKINASE-TYPE PLASMINOGEN-ACTIVATOR, WHEREAS THE CORRESPONDING RAT-CELLS PRODUCE TISSUE-TYPE PLASMINOGEN-ACTIVATOR [J].

CANIPARI, R ;

OCONNELL, ML ;

MEYER, G ;

STRICKLAND, S .

JOURNAL OF CELL BIOLOGY, 1987, 105 (02) :977-981

[19] Kringle 5 of plasminogen is a novel inhibitor of endothelial cell growth [J].

Cao, YH ;

Chen, A ;

An, SSA ;

Ji, RWD ;

Davidson, D ;

Cao, YM ;

Llinas, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (36) :22924-22928

[20] Kringle domains of human angiostatin - Characterization of the anti-proliferative activity on endothelial cells [J].

Cao, YH ;

Ji, RW ;

Davidson, D ;

Schaller, J ;

Marti, D ;

Sohndel, S ;

McCance, SG ;

OReilly, MS ;

Llinas, M ;

Folkman, J .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (46) :29461-29467

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